Introduction
Lidocaine Hydrochloride (CAS 73-78-9), the salt form of Lidocaine, is one of the most widely used local anesthetics and anti-arrhythmic drugs in the modern pharmaceutical industry. As a high-purity Active Pharmaceutical Ingredient (API), Lidocaine HCl is preferred over its base form in many formulations due to its superior water solubility. This guide provides a comprehensive overview of Lidocaine HCl API for pharmaceutical manufacturers and professional buyers.

What is Lidocaine Hydrochloride?
Lidocaine Hydrochloride is a white crystalline powder that acts as a sodium channel blocker. By inhibiting the ionic fluxes required for the initiation and conduction of impulses, it effectively stabilizes the neuronal membrane, leading to local anesthesia. In cardiac applications, it is utilized as a Class Ib anti-arrhythmic agent.

Chemical Properties & CAS Information

• Chemical Name: 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride

• CAS Number: 73-78-9 (Anhydrous) / 6108-05-0 (Monohydrate)

• Molecular Formula: C14H23ClN2O

• Molecular Weight: 270.8 g/mol

• Solubility: Very soluble in water and alcohol; practically insoluble in ether.

Pharmaceutical Specifications (USP / EP / BP)
High-quality Lidocaine HCl API must adhere to international pharmacopeia standards. Our product consistently meets or exceeds:

1. USP (United States Pharmacopeia): Strict limits on bacterial endotoxins and residual solvents.

2. EP (European Pharmacopoeia): Specific requirements for related substances and impurity profiles.

3. BP (British Pharmacopoeia): Standardized acidity and clarity of solution tests.
   Typical Assay: 99.0% - 101.0% on an anhydrous basis.

Packaging & Storage
To maintain the stability of the API, Lidocaine HCl should be stored in a cool, dry, and well-ventilated area, away from direct light and moisture.

• Standard Packaging: 25kg/Fiber Drum with double PE inner bags.

• Shelf Life: 36 months when stored under recommended conditions.

Why Choose Us as Your Lidocaine HCl Supplier?
As a leading Lidocaine HCl manufacturer, we provide more than just a chemical; we provide a foundation for your formulation's success.

• Unmatched Purity: Our advanced crystallization process ensures minimal impurities.

• Full Documentation: We provide COA, MSDS, and support for DMF filings.

• Global Logistics: Efficient shipping with full compliance with international pharmaceutical trade regulations.