- PRODUCT NAME:Apixaban
1.What is Apixaban?
Apixaban, chemically named as 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide, has the molecular formula C25H25N5O4. It possesses a molecular weight of 459.49700, a density of 1.42 g/cm³, a boiling point of 770.468ºC at 760 mmHg, a flash point of 419.764ºC, and a refractive index of 1.705. Clinically, it is utilized in adult patients undergoing elective hip or knee replacement surgery to prevent venous thromboembolism (VTE) events.
2.How it Works?
Apixaban is a potent, orally active, reversible, direct, and highly selective inhibitor of Factor Xa's active site. Its antithrombotic activity does not depend on antithrombin III. Apixaban can inhibit both free and clot-bound Factor Xa, as well as prothrombinase activity. While it does not directly affect platelet aggregation, it indirectly inhibits thrombin-induced platelet aggregation. By inhibiting Factor Xa, Apixaban reduces the generation of thrombin and suppresses thrombus formation. Preclinical studies in animal models have demonstrated that Apixaban exhibits antithrombotic effects at dose levels that do not compromise hemostatic function, effectively preventing both arterial and venous thrombosis.
3.Benefits and Uses
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Prevention of Venous Thromboembolism (VTE): This includes the prevention of blood clots following hip or knee replacement surgery.
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Treatment of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE): As well as the prevention of their recurrence.
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Reduction of Stroke and Systemic Embolism Risk: In patients with non-valvular atrial fibrillation.
4.Q&A
Q:Does the company accept sample orders?
A:Yes, our company accepts sample orders.
Q:What is the minimum order quantity for the company?
A:We do not have a minimum order quantity requirement, we arrange according to the customer's needs.
Q:How to ensure the quality of goods?
A:We have a strict QC/QA management system and strict release procedures, and we will provide all procedures to customers before shipment according to their requirements.
Q:Can we see the product quality before the order is shipped?
A:Of course, we always provide a relative Batach (s) 'COA before shipping.
Q:How will you deliver the goods?
A:We will communicate with customers, adopt their suggestions, arrange the most suitable delivery method, and ensure mutual satisfaction.
