Home >Product >Dapagliflozin
Dapagliflozin
Dapagliflozin
CAS No.:461432-26-8
Molecular Formula:C21H25ClO6
Molecular Weight:408.87
PRODUCT NAME:Dapagliflozin

Introduction: Welcome to the world of Dapagliflozin, a groundbreaking medication designed to enhance diabetes management by inhibiting sodium-glucose cotransporter 2 (SGLT2). Dapagliflozin belongs to the class of sodium-glucose cotransporter 2 inhibitors, which work by reducing glucose reabsorption in the kidneys. This innovative medication offers effective glycemic control and provides numerous benefits for individuals living with type 2 diabetes. Let's delve into the wonders of Dapagliflozin and its impact on diabetes management.

The Power of Dapagliflozin: Dapagliflozin's mechanism of action centers around the kidneys, where it inhibits the reabsorption of glucose. By doing so, it promotes the excretion of excess glucose in the urine, leading to lowered blood glucose levels. This process not only aids in managing hyperglycemia but also offers additional advantages for cardiovascular and renal health.

Benefits of Dapagliflozin:

1:Glycemic Control: Dapagliflozin is a valuable addition to the treatment regimen of individuals with type 2 diabetes, as it helps lower blood glucose levels and improves overall glycemic control.

2:Weight Loss: Dapagliflozin's mechanism of glucose excretion in the urine is associated with modest weight loss, making it particularly beneficial for those aiming to manage body weight.

3:Cardiovascular Benefits: Clinical studies have shown that Dapagliflozin provides cardiovascular benefits by reducing the risk of major adverse cardiovascular events in certain high-risk individuals.

4:Renal Protection: Dapagliflozin has been found to slow the progression of kidney disease and reduce the risk of renal-related complications in patients with type 2 diabetes and pre-existing kidney issues.

5: Convenient Once-Daily Dosage: Dapagliflozin is typically taken once daily, offering a convenient dosing schedule that supports treatment adherence.

 

Batch No.

23010201

Mfg. Date

2023-01-02

Ret. Date

2025-01-01

Rpt. Date

2023-01-09

Source

Workshop

QCS

2020 of Enterprise Standard

 

TESTS

STANDARD

RESULTS

Appearance

White to off-white powder

White powder

Melting point

7280°C

74.7-75.9°C

Optical rotation

+ 13。〜+17°

+ 14.6°

Identification

HPLC RT

Conform

UV

Conform

Water

3.0% 4.4%

3.61%

Residue on ignition

0.10%

0.08%

Heavy metals

20ppm

<20ppm

Chiral impurity

0.15%

0.09%

Perce ntage of propa nediol

13.6% 16.6%

15.3%

 

Methanol<3000ppm

ND

 

Residual solvents

Ethanol5000ppm

ND

Acetonitrile410ppm

ND

Dichloromethane600ppm

ND

Ethyl acetate5000ppm

650ppm

N-Hexane290ppm

146ppm

THF720ppm

ND

Toluene890ppm

ND

Related impurities

Any individual impurity0.10%

0.04%

Total impurities 1.0%

0.16%

Purity

99.0%

99.84%

HPLC assay

98.0%- 102.0%

99.8%

Conclusion: Complies With 2020 of Enterprise Standard

 

Have Questions about Arshine Pharma?
Our professional sales team are waiting for your consultation.

INFORMATION

Sign up to receive our weekly newsletter