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Vonoprazan Fumarate
Vonoprazan Fumarate
CAS No.:1260141-27-2
Molecular Formula:C17H16FN3O2S.C4H4O4
Molecular Weight:461.46
PRODUCT NAME:Vonoprazan Fumarate

Introduction: Welcome to the world of Vonoprazan Fumarate, a groundbreaking medication designed to provide relief and management of acid-related disorders. Vonoprazan Fumarate is a potent proton pump inhibitor (PPI) that offers a novel approach to reducing gastric acid secretion. This innovative medication is a valuable tool in the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions arising from excessive stomach acid production. Let's delve into the benefits and applications of Vonoprazan Fumarate in empowering acid-related disorder management.

The Power of Vonoprazan Fumarate: Vonoprazan Fumarate's mechanism of action centers on inhibiting the H+/K+ ATPase proton pump, an enzyme responsible for the secretion of gastric acid. Unlike traditional PPIs, Vonoprazan Fumarate offers rapid and sustained acid suppression, making it a potent option for managing acid-related disorders.

Benefits of Vonoprazan Fumarate:

1:GERD Relief: Vonoprazan Fumarate is particularly effective in providing relief from the symptoms of gastroesophageal reflux disease (GERD), including heartburn and regurgitation.

2:Peptic Ulcer Healing: Vonoprazan Fumarate aids in the healing and prevention of peptic ulcers by reducing stomach acid secretion and creating an environment conducive to tissue repair.

3:Helicobacter pylori Eradication: In combination with antibiotics, Vonoprazan Fumarate can be used to help eradicate Helicobacter pylori bacteria, a common cause of peptic ulcers.

4:Maintenance Therapy: Vonoprazan Fumarate is suitable for long-term maintenance therapy to prevent recurrence of GERD symptoms or peptic ulcers.

5:Diverse Applications: Vonoprazan Fumarate is a versatile medication that offers benefits in various acid-related disorders, providing relief and improving the quality of life for affected individuals.

Product Name

(E)-but-2-encdioic acid J-[5-(2-fluorophenyl)-1 - pyridin-3-ylsul fbnylpyrrol-3-yl]-N-methylmctha namine

CAS NO.

1260141-27-2

Mfg Date

Apr.06,2023

Batch NO.

2M024230401

Inspection Date

Apr. 13,2023

Production Lot Size

50.55Kg

Report Date

Apr.25,2023

 

Packing Specification

25Kg/drum

 

Retest Date

 

Apr.05,2023

 

Inspection Criteria

Corporate Inner Quality Standards &VolumeIVolumeIVof'C.P (2020version)

 

Inspection Items

Standard

Inspection Result

Conclusion

Description

White or ofF-white crystalline powder

White crystalline powder

Conforms

Water

<0.5%

0.23%

Qualified

Melting Point

196201 °C

197.0 198.1 °C

Qualified

Residue on Ignition

<0.1%

0.02%

Qualified

Heavy Metals

<20ppm

Conforms 符合规定

Conforms

Related substances

Single Impurity <0.1%

0.07%

Qualified

 

Total Impurities<0.5%

0.24%

Qualified

 

Residual solvents

Methanol<0.3%

0.018%

Qualified

N,N-Dimcthylacctamide<0.109%

ND

Qualified

A cctonitrile<0.041 %

ND

Qualified

Assay

99.0% 102.0%

99.60%

 

 

Conclusion

 

Acoording with the standard, it conformed

 

 

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