- PRODUCT NAME:Caffeine
Caffeine API (CAS 58-08-2) – Premium Pharmaceutical Grade
As a world-class caffeine api supplier, Arshine Lifescience is dedicated to providing high-purity caffeine raw material pharmaceutical grade to pharmaceutical manufacturers and healthcare brands globally. Our caffeine cas 58-08-2 is produced in state-of-the-art facilities, ensuring it meets the most rigorous international quality standards.
Compliance with Global Standards: Caffeine USP/EP/BP
Quality is the cornerstone of Arshine Lifescience. We ensure that every batch of our product complies with the latest pharmacopoeia.Whether you are formulating analgesics or respiratory stimulants, our pharmaceutical grade caffeine offers the consistency and safety required for high-end pharmaceutical applications.
Certificate of Analysis (Food Grade)：
| CERTIFICATE OF ANALYSIS | |||||||
| Hebei Guangxiang Pharmaceutical Co.,Ltd. | |||||||
| BG-GX/ZB/04.008-02 Rev06/2024 P1/2 | |||||||
| Name | Anhydrous Caffeine | Manufacture Date | 2024.09.23 | ||||
| Batch No | 2012409090 | Expiry Date | 2029.09.22 | ||||
| Package | 20kg/Carton | Test Date | 2024.09.24 | ||||
| Batch Size | 20000 kg | Reporting time | 2024.10.06 | ||||
| Inspection basis | EP 11.0,BP2023,USP2023,FCC12,CP2020 | ||||||
| Items | Specifications | Results | |||||
| Characters(FCC12) | White or almost white,crystalline powder or silky white or almost white,crystals. |
Complies | |||||
| Solubility(BP2023、EP11.0) | Sparingly soluble in water,freely soluble in boiling water,slightly soluble in ethanol(96%).It dissolves in concentrated solutions of alkali benzoates or salicylates.It sublimes readily. |
Complies | |||||
| Identifications | Identifications A (USP2023) |
The sample spectrum complies with that of the reference standard s p e c t r u m |
Complies | ||||
| Identifications B (USP2023) |
The retention time of the caffeine peak of the sample solution corresponds to that of the standard solution |
Complies | |||||
| Appearance of solution(BP2023、EP11.0) | Solution S is clear and colourless | Complies | |||||
| Acidity(BP2023、EP11.0) | Not more than 0.2mL of 0.01M sodium hydroxide is required to change the colour of the indicator to blue |
Complies | |||||
| Related Substances(BP2023、EP11.0) | Any other impurity≤0.5times the area of solution(a)(0.10%) | 0.03% | |||||
| Total Impurities≤0.5times the area of solution(a)(0.10%) | 0.04% | ||||||
| Melting Point(FCC12) | 235.0-237.5℃ | Complies | |||||
| Sulfates(BP2023、EP11.0) | ≤500ppm | Complies | |||||
| CERTIFICATE OF ANALYSIS | |||||||
| Hebei Guangxiang Pharmaceutical Co.,Ltd. | |||||||
| BG-GX/ZB/04.00802 Rev06/2024 P2/2 | |||||||
| Name | Anhydrous Caffeine | Manufacture Date | 2024.09.23 | ||||
| Batch No | 2012409090 | Expiry Date | 2029.09.22 | ||||
| Package | 20kg/Carton | Test Date | 2024.09.24 | ||||
| Batch Size | 20000kg | Reporting time | 2024.10.06 | ||||
| Inspection basis | EP 11.0,BP2023,USP2023,FCC12,CP2020 | ||||||
| Items | Specifications | Results | |||||
| Water determination(USP2023) | ≤0.5% | 0.1% | |||||
| Sulphated Ash(BP2023、EP¹1.0) | ≤0.1% | 0.06% | |||||
| Organic impurities(USP2023) | Individual impurity≤0.1% | 0.03% | |||||
| Total Impurities≤0.1% | 0.05% | ||||||
| Assay(USP2023) | 99.0%-101.0% | 99.6% | |||||
| Other alkaloids(FCC) | Compliance | Complies | |||||
| Easy carbonization(FCC) | Compliance | Complies | |||||
| Heavy metal(CP) | ≤10ppm | Complies | |||||
| Lead(FCC) |
≤0.5ppm |
Complies | |||||
| Arsenic |
≤1.5ppm |
Complies | |||||
| Mercury | ≤0.1mg/kg | Complies | |||||
| Microbial Limit(CP) | Total aerobic bacteria ≤800cfu/g | Complies | |||||
| Total mold and yeast ≤80cfu/g | Complies | ||||||
| Escherichia coli cannot be detected | Not detected | ||||||
| Coliforms:<10 cfu/g | Not detected | ||||||
| Staphylococcus Aureus Negative/25g | Complies | ||||||
| Total number of colonies<1000 cfu/g | Complies | ||||||
| Salmonella cannot be detected | Not detected | ||||||
| Conclusion:The product complies with Caffeine test method EP11.0,BP2023,USP2023,FCC12,CP2020 | |||||||
Certificate of Analysis (Medicinal caffeine)：
| CERTIFICATE OF ANALYSIS | |||||||
| Hebei Guangxiang Pharmaceutical Co.,Ltd. | |||||||
| BG-GX/ZB/04.107-02 Rev01/2023 PI/2 | |||||||
| Name | Medicinal caffeine | ||||||
| Batch No | 2012312051 | Manufacture Date | 2023/12/29 | ||||
| Certificate No | C231229004 | Expiry Date | 2028/12/28 | ||||
| Package | 20kg/box | Test Date | 2023/12/29 | ||||
| Batch Size | 2000kg | Reporting time | 2024/10/12 | ||||
| Inspection basis | EP11.0 | ||||||
| Items | Specifications | Results | |||||
| Characters | White or neariy white,crystalline powder or filamentous crystals. |
Complies | |||||
| Identifications | Melting Point | 234-239℃ | Complies | ||||
| IR | The sample spectrum complies with that of the reference standard spectrum. |
Complies | |||||
| Second Identifications C |
Positive reaction | Complies | |||||
| Second Identifications D |
Positive reaction | Complies | |||||
| Second Identifications F |
Positive reaction | Complies | |||||
| Appearane of solution | Solution S is clear and colourless | Complies | |||||
| Acidity | Should compiy with regulations | Complies | |||||
| Sulfates | ≤500ppm | Complies | |||||
| CERTIFICATE OF ANALYSIS | |||||||
| Hebei Guangxiang Pharmaceutical Co.,Ltd. | |||||||
| BG-GX/ZB/04.107-02 Rev01/2023 P2/2 | |||||||
| Name | Medicinal caffeine | ||||||
| Batch No | 2012312051 | Manufacture Date | 2023/12/29 | ||||
| Certificate No | C231229004 | Expiry Date | 2028/12/28 | ||||
| Package | 20kg/Box | Test Date | 2023/12/29 | ||||
| Batch Size | 2000kg | Reporting time | 2024/10/12 | ||||
| Inspection basis | EP 11.0 | ||||||
| Items | Specifications | Results | |||||
| Related Substances | Single impurity≤0.10% | 0.02% | |||||
| Totai misceiianeous≤0.10% | 0.03% | ||||||
| Loss on Drying | ≤0.5% | 0.06% | |||||
| Sulphated Ash | ≤0.1% | 0.06% | |||||
| Assay | 98.5%-101.5% | 99.8% | |||||
| Residual amount of dimethyl sulfate | ≤3.75ppm | Not detected | |||||
| Conclusion:The product complies with EP 11.0 | |||||||
Why Arshine Lifescience is Your Preferred Caffeine API Supplier?
When you choose to buy caffeine api from Arshine, you benefit from our extensive industry expertise and global logistics network:
Strict Quality Control: Our QC team ensures every gram of caffeine raw material pharmaceutical meets international benchmarks.
Global Supply Chain: We maintain strong relationships with top-tier caffeine cas 58-08-2 manufacturer bases to ensure stable pricing and supply.
Regulatory Support: Arshine provides complete dossier support to help you navigate complex registration processes in different markets.
Key Applications of Pharmaceutical Grade Caffeine
Our API is widely utilized in the production of:
Combined Analgesics (e.g., with Paracetamol or Aspirin).
Anti-fatigue and Alertness medications.
Therapeutic formulations for neonatal apnea.
High-end nutraceuticals and functional supplements.
Contact Arshine Lifescience to Buy Caffeine API
Looking for a competitive quote or a sample? Arshine Lifescience simplifies the process to buy caffeine api. Our team of experts is ready to provide you with the latest market trends and technical data.
